LOD score

{
  "id": "MLC-T-CHM-006747",
  "term": "LOD score",
  "field": "Chemistry",
  "definition": "A statistical estimate of the likelihood of genetic linkage between two loci, such as a disease gene and a genetic marker. It is the logarithm (base 10) of the ratio of the probability of observing the pedigree data if the two loci are linked, to the probability if they are unlinked. A LOD score of 3 or greater is generally considered evidence for linkage.",
  "synonyms": [
    "logarithm (base 10) of odds"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "linkage analysis",
    "locus"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 773 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/lod-score/"
}