lidocaine hydrochloride ophthalmic gel

{
  "id": "MLC-T-ONC-014777",
  "term": "lidocaine hydrochloride ophthalmic gel",
  "field": "Oncology and biomedicine",
  "definition": "An ophthalmic gel formulation containing the synthetic amide-type anesthetic lidocaine, with potential analgesic activity. Upon ophthalmic application, the active ingredient lidocaine binds to and blocks voltage-gated sodium channels in neuronal cell membranes. Lidocaine-mediated stabilization of neuronal membranes inhibits the initiation and conduction of nerve impulses, which numbs the nerves, prevents the trigemino-cardiac reflex and produces a reversible local anesthesia.",
  "synonyms": [
    "lidocaine HCl ophthalmic gel"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/lidocaine-hydrochloride-ophthalmic-gel/"
}