Melan-A VLP vaccine
Term · Oncology and biomedicine · MLC-T-ONC-015074
A vaccine consisting of the melanocyte differentiation antigen Melan A (also called MART-1) encapsulated in noninfectious virus-like particles (VLPs) with potential immunostimulating and antineoplastic activities. Upon administration, Melan-A VLP vaccine may stimulate the immune system to exert a specific cytotoxic T lymphocyte (CTL) response against tumor cells expressing the Melan A antigen, resulting in tumor cell lysis. Melan A is upregulated in most melanomas. VLPs stimulate the immune system and promotes the CTL response.
| Identifier | MLC-T-ONC-015074 |
|---|---|
| Field | Oncology and biomedicine |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-015074",
"term": "Melan-A VLP vaccine",
"field": "Oncology and biomedicine",
"definition": "A vaccine consisting of the melanocyte differentiation antigen Melan A (also called MART-1) encapsulated in noninfectious virus-like particles (VLPs) with potential immunostimulating and antineoplastic activities. Upon administration, Melan-A VLP vaccine may stimulate the immune system to exert a specific cytotoxic T lymphocyte (CTL) response against tumor cells expressing the Melan A antigen, resulting in tumor cell lysis. Melan A is upregulated in most melanomas. VLPs stimulate the immune system and promotes the CTL response.",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/melan-a-vlp-vaccine/"
}
Record 10,790 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.