MLchartDataset catalogue

Matuzumab

Term · Oncology and biomedicine · MLC-T-ONC-015025

A humanized monoclonal antibody with antineoplastic activity. Matuzumab binds the epidermal growth factor receptor (EGFR) with high affinity, competitively blocking natural ligand binding and blocking receptor-mediated downstream signalling, resulting in impaired tumor cell proliferation.

Table 1. Record
IdentifierMLC-T-ONC-015025
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-015025",
  "term": "Matuzumab",
  "field": "Oncology and biomedicine",
  "definition": "A humanized monoclonal antibody with antineoplastic activity. Matuzumab binds the epidermal growth factor receptor (EGFR) with high affinity, competitively blocking natural ligand binding and blocking receptor-mediated downstream signalling, resulting in impaired tumor cell proliferation.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/matuzumab/"
}

Record 10,673 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.