Methoxsalen

{
  "id": "MLC-T-ONC-005322",
  "term": "Methoxsalen",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used together with UV light to treat psoriasis, vitiligo, and skin nodules of cutaneous T-cell lymphoma. It is also being studied in the treatment of graft-versus-host disease. It belongs to the family of drugs called psoralens and furocoumarins.",
    "A naturally occurring substance isolated from the seeds of the plant Ammi majus with photoactivating properties. As a member of the family of compounds known as psoralens or furocoumarins, methoxsalen's exact mechanism of action is unknown; upon photoactivation, methoxsalen has been observed to bind covalently to and crosslink DNA."
  ],
  "abbreviation": "8-MOP",
  "synonyms": [
    "8-methoxypsoralen",
    "Methoxypsoralen"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/methoxsalen/"
}