Methylmercaptopurine riboside
Term · Oncology and biomedicine · MLC-T-ONC-015137
A purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside (6-MMPR) inhibits amidophosphoribosyltransferase, the first committed step in de novo purine synthesis, and inhibits fibroblast growth factor-2 (FGF2)-induced cell proliferation.
| Identifier | MLC-T-ONC-015137 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | MMPR |
| Synonyms | methylthioinosine |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-015137",
"term": "Methylmercaptopurine riboside",
"field": "Oncology and biomedicine",
"definition": "A purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside (6-MMPR) inhibits amidophosphoribosyltransferase, the first committed step in de novo purine synthesis, and inhibits fibroblast growth factor-2 (FGF2)-induced cell proliferation.",
"abbreviation": "MMPR",
"synonyms": [
"methylthioinosine"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/methylmercaptopurine-riboside/"
}
Record 10,953 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.