MLchartDataset catalogue

methoxyflurane

Term · Oncology and biomedicine · MLC-T-ONC-015131

A fluorinated isopropyl ether with anesthetic and muscle relaxant activities. Although the mechanism of action has not been fully elucidated, upon inhalation, methoxyflurane acts through multiple mechanisms of action. This agent interferes with the release and re-uptake of neurotransmitters at post-synaptic terminals, and/or alters ionic conductance following receptor activation by a neurotransmitter, thereby disrupting neuronal transmission. In addition, this agent activates the inhibitory receptor gamma-aminobutyric acid (GABA). Altogether, this results in a general anesthetic effect and induces analgesia.

Table 1. Record
IdentifierMLC-T-ONC-015131
FieldOncology and biomedicine
Synonymsanalgizer; methoflurane
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-015131",
  "term": "methoxyflurane",
  "field": "Oncology and biomedicine",
  "definition": "A fluorinated isopropyl ether with anesthetic and muscle relaxant activities. Although the mechanism of action has not been fully elucidated, upon inhalation, methoxyflurane acts through multiple mechanisms of action. This agent interferes with the release and re-uptake of neurotransmitters at post-synaptic terminals, and/or alters ionic conductance following receptor activation by a neurotransmitter, thereby disrupting neuronal transmission. In addition, this agent activates the inhibitory receptor gamma-aminobutyric acid (GABA). Altogether, this results in a general anesthetic effect and induces analgesia.",
  "synonyms": [
    "analgizer",
    "methoflurane"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/methoxyflurane/"
}

Record 10,945 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.