MART-1:26-35(27L) peptide vaccine

{
  "id": "MLC-T-ONC-015013",
  "term": "MART-1:26-35(27L) peptide vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A peptide-based cancer vaccine consisting of amino acid residues 26 through 35 of MART-1 (melanoma antigen recognized by T-cells-1) with a leucine substitution at amino acid position 27 to improve immunogenicity. Upon administration, MART-1:26-35(27L) peptide vaccine may induce a cytotoxic T-lymphocyte (CTL) response against MART-1-expressing tumor cells, resulting in decreased tumor growth. The tumor-associated antigen (TAA) MART-1 may be overexpressed on melanoma cancer cells.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/mart-1-26-35-27l-peptide-vaccine/"
}