Golimumab

{
  "id": "MLC-T-ONC-014003",
  "term": "Golimumab",
  "field": "Oncology and biomedicine",
  "definition": "A human monoclonal antibody directed against the pro-inflammatory cytokine tumor necrosis factor-alpha (TNF-a) with immunosuppressive activity. Golimumab binds to TNF-a, thereby preventing TNF-a-mediated immune responses. TNF-a production is dysregulated in various auto-immune diseases and in cancer.",
  "synonyms": [
    "immunoglobulin G1, anti-(human Tumor Necrosis Factor Alpha) (human monoclonal CNTO 148 gamma-1-chain), disulfide with human monoclonal CNTO 148 kappa-chain, dimer"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/golimumab/"
}