Gallium Ga 68-WL12

{
  "id": "MLC-T-ONC-013889",
  "term": "Gallium Ga 68-WL12",
  "field": "Oncology and biomedicine",
  "definition": "A radiotracer composed of the programmed cell death-1 ligand 1 (PD-L1; cluster of differentiation 274; CD274)-binding peptide WL12 radiolabeled with the radionuclide gallium Ga 68, with potential PD-L1 imaging activity using positron emission tomography (PET). Upon administration of gallium Ga 68-WL12, the WL12 moiety targets and binds to PD-L1 expressed on certain tumor cells. Upon uptake and PET imaging, the radioisotope moiety can be visualized and the extent of PD-L1 expression can be assessed. This may be used to predict the therapeutic response to PD-L1-targeting agents.",
  "synonyms": [
    "68Ga-WL12",
    "gallium Ga 68-labeled WL12",
    "[68Ga]-WL12"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gallium-ga-68-wl12/"
}