glycosylated recombinant human G-CSF AVI-014

{
  "id": "MLC-T-ONC-013987",
  "term": "glycosylated recombinant human G-CSF AVI-014",
  "field": "Oncology and biomedicine",
  "definition": "A glycosylated form of a recombinant agent that is chemically identical to or similar to endogenous human granulocyte colony-stimulating factor (G-CSF) and is produced using transgenic biotechnology. Transgenic hens carrying recombinant human G-CSF cDNA express the naturally glycosylated recombinant human protein in egg albumen from which glycosylated recombinant human G-CSF AVI-014 is isolated. Produced endogenously by monocytes, fibroblasts, and endothelial cells, G-CSF binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions.",
  "abbreviation": "glycosylated rhG-CSF AVI014",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/glycosylated-recombinant-human-g-csf-avi-014/"
}