gallium Ga 68 AIP-301

{
  "id": "MLC-T-ONC-013820",
  "term": "gallium Ga 68 AIP-301",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of AIP-301, a molecule targeting the tumor-associated antigen (TAA) epidermal growth factor receptor 2 (HER2, EGFR2, ERBB2), that is linked to the radionuclide gallium (Ga) 68, with potential use in diagnostic imaging using positron emission tomography/computed tomography (PET/CT). Upon administration of gallium Ga 68 AIP-301, the AIP-301 moiety targets and binds to HER2-expressing tumor cells. This facilitates both the detection of HER2-expressing tumor cells and the assessment of responses to AIP-303 and other HER2-targeted chemotherapeutic agents during PET/CT. HER2, a tyrosine kinase, is overexpressed on the cell surfaces of various tumor cell types.",
  "synonyms": [
    "68Ga-AIP-301",
    "68Ga-AIP301",
    "68Ga-AIP 301",
    "gallium Ga 68 AIP301",
    "gallium Ga 68 AIP 301"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gallium-ga-68-aip-301/"
}