Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH conjugate vaccine
Term · Oncology and biomedicine · MLC-T-ONC-013967
A heptavalent vaccine consisting of the tumor-associated carbohydrate antigens globohexaosylceramide (globo-H), GM2, Lewis-y, MUC1-32(aa), sTn(c), TF(c), and Tn(c) conjugated with keyhole limpet hemocyanin (KLH), an immunomodulator. This vaccine may induce the production of IgG and IgM antibodies and an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing these antigens.
| Identifier | MLC-T-ONC-013967 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | GLO-GM2-LE-MUC1-sTN-TF-TN-KLH |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013967",
"term": "Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH conjugate vaccine",
"field": "Oncology and biomedicine",
"definition": "A heptavalent vaccine consisting of the tumor-associated carbohydrate antigens globohexaosylceramide (globo-H), GM2, Lewis-y, MUC1-32(aa), sTn(c), TF(c), and Tn(c) conjugated with keyhole limpet hemocyanin (KLH), an immunomodulator. This vaccine may induce the production of IgG and IgM antibodies and an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing these antigens.",
"abbreviation": "GLO-GM2-LE-MUC1-sTN-TF-TN-KLH",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/globo-h-gm2-lewis-y-muc1-32-aa-stn-c-tf-c-tn-c-klh-conjugate-vaccine/"
}
Record 8,029 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.