MLchartDataset catalogue

Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH conjugate vaccine

Term · Oncology and biomedicine · MLC-T-ONC-013967

A heptavalent vaccine consisting of the tumor-associated carbohydrate antigens globohexaosylceramide (globo-H), GM2, Lewis-y, MUC1-32(aa), sTn(c), TF(c), and Tn(c) conjugated with keyhole limpet hemocyanin (KLH), an immunomodulator. This vaccine may induce the production of IgG and IgM antibodies and an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing these antigens.

Table 1. Record
IdentifierMLC-T-ONC-013967
FieldOncology and biomedicine
AbbreviationGLO-GM2-LE-MUC1-sTN-TF-TN-KLH
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013967",
  "term": "Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH conjugate vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A heptavalent vaccine consisting of the tumor-associated carbohydrate antigens globohexaosylceramide (globo-H), GM2, Lewis-y, MUC1-32(aa), sTn(c), TF(c), and Tn(c) conjugated with keyhole limpet hemocyanin (KLH), an immunomodulator. This vaccine may induce the production of IgG and IgM antibodies and an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing these antigens.",
  "abbreviation": "GLO-GM2-LE-MUC1-sTN-TF-TN-KLH",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/globo-h-gm2-lewis-y-muc1-32-aa-stn-c-tf-c-tn-c-klh-conjugate-vaccine/"
}

Record 8,029 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.