MLchartDataset catalogue

GM2-KLH vaccine

Term · Oncology and biomedicine · MLC-T-ONC-003604

  1. A substance used to stimulate the production of antibodies that fight certain cancer cells.

  2. A cancer vaccine consisting of GM2 ganglioside, a melanoma-specific antigen, conjugated with the immunostimulant keyhole limpet hemocyanin. Vaccination with GM2-KLH vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against GM2 ganglioside-expressing melanoma cells, resulting in tumor growth inhibition.

Table 1. Record
IdentifierMLC-T-ONC-003604
FieldOncology and biomedicine
AbbreviationGM2-KLH
SynonymsGM2-KLH ganglioside; KLH-conjugated GM2 Ganglioside Vaccine
ReferencesNCI Dictionary of Cancer Terms; National Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-003604",
  "term": "GM2-KLH vaccine",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A substance used to stimulate the production of antibodies that fight certain cancer cells.",
    "A cancer vaccine consisting of GM2 ganglioside, a melanoma-specific antigen, conjugated with the immunostimulant keyhole limpet hemocyanin. Vaccination with GM2-KLH vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against GM2 ganglioside-expressing melanoma cells, resulting in tumor growth inhibition."
  ],
  "abbreviation": "GM2-KLH",
  "synonyms": [
    "GM2-KLH ganglioside",
    "KLH-conjugated GM2 Ganglioside Vaccine"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gm2-klh-vaccine/"
}

Record 8,086 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.