anti-ganglioside GM2 monoclonal antibody BIW-8962

{
  "id": "MLC-T-ONC-010678",
  "term": "anti-ganglioside GM2 monoclonal antibody BIW-8962",
  "field": "Oncology and biomedicine",
  "definition": "A humanized anti-ganglioside GM2 (GM2) monoclonal antibody with potential antineoplastic and immunomodulating activities. Upon administration, anti-ganglioside GM2 monoclonal antibody BIW-8962 may activate an antibody dependent cellular cytotoxicity (ADCC) against GM2-expressing tumor cells. GM2 is a tumor associated antigen (TAA) overexpressed on the surface of many cancer cells, such as multiple myeloma (MM) cells and neuroblastoma cells.",
  "synonyms": [
    "anti-GM2 monoclonal antibody BIW-8962"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-ganglioside-gm2-monoclonal-antibody-biw-8962/"
}