monoclonal antibody 14G2A

{
  "id": "MLC-T-ONC-015245",
  "term": "monoclonal antibody 14G2A",
  "field": "Oncology and biomedicine",
  "definition": "A murine monoclonal antibody directed against the ganglioside GD2 with potential antineoplastic activity. Monoclonal antibody 14G2A binds to the ganglioside GD2 and induces antibody-dependent cell mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. GD2 is overexpressed in malignant melanoma, neuroblastoma, osteosarcoma, and small cell carcinoma of the lung.",
  "abbreviation": "MOAB 14G2A",
  "synonyms": [
    "14G2A",
    "14G2A, monoclonal antibody",
    "antibody 14G2A, monoclonal"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/monoclonal-antibody-14g2a/"
}