iodine I 124 monoclonal antibody 3F8

{
  "id": "MLC-T-ONC-014508",
  "term": "iodine I 124 monoclonal antibody 3F8",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate consisting of 3F8, a murine anti-GD2 ganglioside monoclonal antibody labeled with iodine I 124 (I-124), with radioimaging activity using positron emission tomography (PET). Upon intravenous administration of iodine I 124 monoclonal antibody 3F8, the 3F8 moiety binds to GD2 expressed on tumor cells. This binding enables both PET imaging via iodine I 124 and the visualization of GD2-expressing tumor cells. GD2 is a ganglioside overexpressed in a variety of cancer cells, including neuroblastoma cells.",
  "abbreviation": "I 124 mAb 3F8",
  "synonyms": [
    "I 124 monoclonal antibody 3F8",
    "124I-humanized 3F8"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iodine-i-124-monoclonal-antibody-3f8/"
}