Iodine I 124 CPD-1028

{
  "id": "MLC-T-ONC-014502",
  "term": "Iodine I 124 CPD-1028",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of the insulin-like growth factor 1 receptor (IGF-1R) binding agent CPD-1028 and conjugated to the radionuclide iodine I 124, with potential tumor imaging properties upon positron emission tomography/computed tomography (PET/CT). Upon administration, iodine I 124 CPD-1028 targets and binds to IGF-1R-expressing tumor cells. Upon PET/CT imaging, the iodine I 124 moiety can be visualized and the quantity of IGF-1R-expressing tumor cells can be assessed. IGF-1R, a receptor tyrosine kinase overexpressed in a variety of human cancers, plays a significant role in the stimulation of cellular proliferation, oncogenic transformation, and the suppression of apoptosis.",
  "abbreviation": "[I-124]-CPD-1028",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iodine-i-124-cpd-1028/"
}