Iodine I 124 iobenguane

{
  "id": "MLC-T-ONC-014505",
  "term": "Iodine I 124 iobenguane",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of the positron-emitting radioisotope iodine I 124 labeled to iobenguane, the synthetic aralkylguanidine analogue of the neurotransmitter norepinephrine (NE), with potential diagnostic imaging applications upon positron emitting tomography (PET) or computed tomography (CT). Upon administration, iodine I 124 iobenguane is taken up and accumulates in the granules of adrenal medullary chromaffin cells and in the pre-synaptic granules of adrenergic neurons in a manner almost identical with that of NE. In turn, tumor cells can be imaged upon PET or CT.",
  "abbreviation": "124I-MIBG",
  "synonyms": [
    "iodine I 124 metaiodobenzylguanidine",
    "iobenguane I-124"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iodine-i-124-iobenguane/"
}