Iodine I 124 monoclonal antibody M5A

{
  "id": "MLC-T-ONC-014510",
  "term": "Iodine I 124 monoclonal antibody M5A",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate comprised of M5A, a humanized monoclonal antibody directed against carcinoembryonic antigen-related cell adhesion molecule 5 (CEA or CEACAM5), labeled with iodine I 124 (I-124) with potential radiolocalization applications. Upon administration, the antibody moiety of iodine I 124 monoclonal antibody M5A specifically binds to cells expressing CEA. Upon binding, the radioisotope moiety can be detected using positron-emission tomography (PET), thereby allowing the imaging and quantification of CEA-expressing tumor cells. CEA, a tumor associated antigen and a member of the CEA family of proteins, plays a key role in cell migration, cell invasion, and cell adhesion and is overexpressed by a variety of cancer types.",
  "synonyms": [
    "iodine I 124 anti-CEA monoclonal antibody M5A",
    "124I-M5A"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iodine-i-124-monoclonal-antibody-m5a/"
}