iodine I 124 iodo-azomycin galactopyranoside

{
  "id": "MLC-T-ONC-014506",
  "term": "iodine I 124 iodo-azomycin galactopyranoside",
  "field": "Oncology and biomedicine",
  "definition": "A diagnostic radiopharmaceutical comprised of iodo-azomycin galactopyranoside (IAZGP) labeled with the positron-emitting radioisotope iodine I 124 and used as an imaging agent. Iodine I 124 iodo-azomycin galactopyranoside (I-124 IAZGP) is reduced under hypoxic conditions, covalently binding to macromolecules in hypoxic cells. After incorporation into hypoxic tumor cell DNA, I-124 IAZGP can be localized and quantified using positron emission tomography (PET), allowing a quantitative assessment of hypoxic tumor burden. IAZGP appears to have a higher water solubility and faster clearance from normal tissue than traditional imidazole tracers.",
  "abbreviation": "I-124 IAZGP",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iodine-i-124-iodo-azomycin-galactopyranoside/"
}