iodine I 124 monoclonal antibody A33

{
  "id": "MLC-T-ONC-014509",
  "term": "iodine I 124 monoclonal antibody A33",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate of a humanized monoclonal antibody (MoAb) A33 labelled with iodine 124 (I-124). MoAb A33 recognizes A33 antigen, a 43 KDa transmembrane glycoprotein of the immunoglobulin superfamily, highly and homogenously expressed in 95% of colorectal cancer metastases, with only restricted expression in normal colonic mucosa. I-124 MoAb A33 delivers beta particle emitting I-124 nuclide directly to metastatic colorectal tissues, thereby this agent could be used in kinetics studies or radioimmunotherapy.",
  "synonyms": [
    "I 124 Monoclonal Antibody A33",
    "iodine I 124 MOAB A33"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iodine-i-124-monoclonal-antibody-a33/"
}