MLchartDataset catalogue

iodine I 131 monoclonal antibody 3F8

Term · Oncology and biomedicine · MLC-T-ONC-014528

A radioimmunoconjugate consisting of 3F8, a murine anti-GD2 ganglioside monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic properties. Using monoclonal antibody 3F8 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing GD2. GD2 is a ganglioside which is overexpressed in malignant melanoma, neuroblastoma, and small cell carcinoma of the lung.

Table 1. Record
IdentifierMLC-T-ONC-014528
FieldOncology and biomedicine
SynonymsI131-MOAB-3F8; iodine I 131 MOAB 3F8; I 131 Monoclonal Antibody 3F8
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-014528",
  "term": "iodine I 131 monoclonal antibody 3F8",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate consisting of 3F8, a murine anti-GD2 ganglioside monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic properties. Using monoclonal antibody 3F8 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing GD2. GD2 is a ganglioside which is overexpressed in malignant melanoma, neuroblastoma, and small cell carcinoma of the lung.",
  "synonyms": [
    "I131-MOAB-3F8",
    "iodine I 131 MOAB 3F8",
    "I 131 Monoclonal Antibody 3F8"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iodine-i-131-monoclonal-antibody-3f8/"
}

Record 9,509 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.