iodine I 131 monoclonal antibody 3F8
Term · Oncology and biomedicine · MLC-T-ONC-014528
A radioimmunoconjugate consisting of 3F8, a murine anti-GD2 ganglioside monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic properties. Using monoclonal antibody 3F8 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing GD2. GD2 is a ganglioside which is overexpressed in malignant melanoma, neuroblastoma, and small cell carcinoma of the lung.
| Identifier | MLC-T-ONC-014528 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | I131-MOAB-3F8; iodine I 131 MOAB 3F8; I 131 Monoclonal Antibody 3F8 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-014528",
"term": "iodine I 131 monoclonal antibody 3F8",
"field": "Oncology and biomedicine",
"definition": "A radioimmunoconjugate consisting of 3F8, a murine anti-GD2 ganglioside monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic properties. Using monoclonal antibody 3F8 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing GD2. GD2 is a ganglioside which is overexpressed in malignant melanoma, neuroblastoma, and small cell carcinoma of the lung.",
"synonyms": [
"I131-MOAB-3F8",
"iodine I 131 MOAB 3F8",
"I 131 Monoclonal Antibody 3F8"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/iodine-i-131-monoclonal-antibody-3f8/"
}
Record 9,509 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.