MLchartDataset catalogue

iodine I 131 monoclonal antibody 81C6

Term · Oncology and biomedicine · MLC-T-ONC-014529

A radioimmunoconjugate consisting of 81C6, a murine IgG2 anti-tenascin monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic activities. Using monoclonal antibody 81C6 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing tenascin. Tenascin is an extracellular matrix protein which is overexpressed in gliomas and other cancers.

Table 1. Record
IdentifierMLC-T-ONC-014529
FieldOncology and biomedicine
Synonymsiodine I 131 MOAB 81C6; I 131 Monoclonal Antibody 81C6
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-014529",
  "term": "iodine I 131 monoclonal antibody 81C6",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate consisting of 81C6, a murine IgG2 anti-tenascin monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic activities. Using monoclonal antibody 81C6 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing tenascin. Tenascin is an extracellular matrix protein which is overexpressed in gliomas and other cancers.",
  "synonyms": [
    "iodine I 131 MOAB 81C6",
    "I 131 Monoclonal Antibody 81C6"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iodine-i-131-monoclonal-antibody-81c6/"
}

Record 9,510 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.