iodine I 131 monoclonal antibody 81C6
Term · Oncology and biomedicine · MLC-T-ONC-014529
A radioimmunoconjugate consisting of 81C6, a murine IgG2 anti-tenascin monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic activities. Using monoclonal antibody 81C6 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing tenascin. Tenascin is an extracellular matrix protein which is overexpressed in gliomas and other cancers.
| Identifier | MLC-T-ONC-014529 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | iodine I 131 MOAB 81C6; I 131 Monoclonal Antibody 81C6 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-014529",
"term": "iodine I 131 monoclonal antibody 81C6",
"field": "Oncology and biomedicine",
"definition": "A radioimmunoconjugate consisting of 81C6, a murine IgG2 anti-tenascin monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic activities. Using monoclonal antibody 81C6 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing tenascin. Tenascin is an extracellular matrix protein which is overexpressed in gliomas and other cancers.",
"synonyms": [
"iodine I 131 MOAB 81C6",
"I 131 Monoclonal Antibody 81C6"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/iodine-i-131-monoclonal-antibody-81c6/"
}
Record 9,510 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.