At 211 monoclonal antibody 81C6

{
  "id": "MLC-T-ONC-011269",
  "term": "At 211 monoclonal antibody 81C6",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate of a human-murine chimeric IgG2 monoclonal antibody (MoAb) 81C6 labeled with an alpha-emitting radionuclide Astatine 211 (At-211), with imaging and radioimmunotherapeutic properties. MoAb 81C6 recognizes the extracellular matrix antigen tenascin (hexabrachion), which is up-regulated in gliomas and other cancers. Using MoAb 81C6 as a carrier for At-211 results in the targeted imaging and/or destruction of cells expressing tenascin.",
  "synonyms": [
    "astatine 211 conjugated 81C6 anti-tenascin monoclonal antibody",
    "astatine At 211 MOAB 81C6",
    "astatine At 211 monoclonal antibody 81C6",
    "astatine-211 labelled anti-tenascin monoclonal antibody 81C6"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/at-211-monoclonal-antibody-81c6/"
}