iodine I 131 monoclonal antibody CC49-deltaCH2

{
  "id": "MLC-T-ONC-014530",
  "term": "iodine I 131 monoclonal antibody CC49-deltaCH2",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate consisting of the humanized CH2 domain-deleted monoclonal antibody CC49 and iodine I 131 with antineoplastic activity. Monoclonal antibody CC49-deltaCH2 targets the tumor-associated glycoprotein 72 (TAG-72) that is expressed by a wide range of human neoplasms including colorectal, gastric, pancreatic, ovarian, endometrial, breast, non-small cell lung, and prostate cancers. Iodine I 131 monoclonal antibody CC49-deltaCH2 binds to tumor cells expressing TAG-72, selectively delivering a cytotoxic dose of beta and gamma radiation.",
  "abbreviation": "131I-MOAB CC49-deltaCH2",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iodine-i-131-monoclonal-antibody-cc49-deltach2/"
}