I 131 monoclonal antibody CC49

{
  "id": "MLC-T-ONC-014283",
  "term": "I 131 monoclonal antibody CC49",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate of the humanized monoclonal antibody CC49 labeled with iodine I 131. Iodine I 131 monoclonal antibody CC49 delivers beta and gamma radiation-emitting I 131 radionuclide specifically to tumor cells that express tumor-associated glycoprotein (TAG)-72, allowing localization of TAG-72-expressing tumor cells with radioimaging devices in diagnostic applications or resulting in specific TAG-72-expressing tumor cell radiocytotoxicity in therapeutic applications. Monoclonal antibody CC49 binds to TAG-72, a pancarcinoma antigen, with high affinity.",
  "abbreviation": "131I-MOAB CC49",
  "synonyms": [
    "iodine I 131 monoclonal antibody CC49",
    "I131 MOAB CC49"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/i-131-monoclonal-antibody-cc49/"
}