Iodine I 131 rituximab

{
  "id": "MLC-T-ONC-014536",
  "term": "Iodine I 131 rituximab",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate comprised of rituximab, a recombinant chimeric monoclonal antibody directed against the CD20 antigen, and labeled with iodine I 131 with potential antineoplastic activity. The antibody moiety of iodine I 131 rituximab binds to the CD20 antigen thereby delivering cytotoxic iodine I 131 specifically to cancer cells expressing CD20. The CD20 antigen, a hydrophobic transmembrane protein, is expressed on normal pre-B and mature B lymphocytes.",
  "synonyms": [
    "131I-Rituxan",
    "131I-rituximab",
    "(131)I-rituximab"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iodine-i-131-rituximab/"
}