Rituximab conjugate CON-4619

{
  "id": "MLC-T-ONC-016558",
  "term": "Rituximab conjugate CON-4619",
  "field": "Oncology and biomedicine",
  "definition": "A proprietary conjugate of rituximab, a recombinant chimeric murine/human antibody directed against the CD20 antigen, with potential antineoplastic activity. Upon administration of the rituximab conjugate CON-4619, the rituximab moiety targets and binds to CD20, a hydrophobic transmembrane protein located on normal pre-B and mature B lymphocytes. Following binding, rituximab triggers a host cytotoxic immune response against CD20-positive cells.",
  "synonyms": [
    "aurixim antibody conjugate"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/rituximab-conjugate-con-4619/"
}