anti-CD20 monoclonal antibody SCT400

{
  "id": "MLC-T-ONC-010293",
  "term": "anti-CD20 monoclonal antibody SCT400",
  "field": "Oncology and biomedicine",
  "definition": "A chimeric monoclonal antibody directed against human CD20, with potential antineoplastic activity. Anti-CD20 monoclonal antibody SCT400 binds to the B cell-specific cell surface antigen CD20, which triggers an immune response against CD20-positive B-cells, leading to apoptosis. CD20, a non-glycosylated cell surface phosphoprotein, is exclusively expressed on B-cells during most stages of B-cell development and is often overexpressed in B-cell malignancies.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-cd20-monoclonal-antibody-sct400/"
}