anti-CD20 CAR T cells C-CAR066

{
  "id": "MLC-T-ONC-010288",
  "term": "anti-CD20 CAR T cells C-CAR066",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous T lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) cluster of differentiation 20 (CD20), with potential immunostimulating and antineoplastic activities. Upon administration, C-CAR066 specifically recognize and kill CD20-expressing tumor cells. The CD20 antigen, a non-glycosylated cell surface phosphoprotein, is a B-cell specific cell surface antigen expressed in B-cell lineage malignancies and certain melanoma cell subpopulations.",
  "synonyms": [
    "CBM.CD20 CAR T C-CAR066",
    "autologous anti-CD20 CAR T cells C-CAR066"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-cd20-car-t-cells-c-car066/"
}