allogeneic anti-CD20 CAR T cells LUCAR-20SP

{
  "id": "MLC-T-ONC-009813",
  "term": "allogeneic anti-CD20 CAR T cells LUCAR-20SP",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of donor-derived T lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) cluster of differentiation 20 (CD20), with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic anti-CD20 CAR T cells LUCAR-20SP specifically recognize and kill CD20-expressing tumor cells. CD20, a non-glycosylated cell surface phosphoprotein, is a B-cell specific cell surface antigen expressed in B-cell lineage malignancies.",
  "synonyms": [
    "allogeneic anti-CD20 CAR-T cells LUCAR-20SP"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/allogeneic-anti-cd20-car-t-cells-lucar-20sp/"
}