Iodine I 131-tositumomab

{
  "id": "MLC-T-ONC-004495",
  "term": "Iodine I 131-tositumomab",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used with another drug to treat certain types of B-cell non-Hodgkin lymphoma. It is also being studied in the treatment of other types of cancer. Iodine I 131-tositumomab is a form of the monoclonal antibody tositumomab that is linked to the radioactive substance iodine I 131. It is a type of radioimmunoconjugate.",
    "A monoclonal antibody directed against the CD20 protein expressed on the surface of B-lymphocytes and radiolabeled with the radioisotope iodine I 131 with potential antineoplastic activity. Iodine I 131 tositumomab binds to and selectively delivers cyctotoxic radiation to CD20-expressing B-lymphocytes, thereby minimizing systemic radiotoxicity."
  ],
  "abbreviation": "I131-MOAB-B1",
  "synonyms": [
    "131-I-anti-B1 monoclonal antibody",
    "I 131 monoclonal antibody anti-B1",
    "I 131 tositumomab",
    "iodine I 131 MOAB anti-B1",
    "iodine I 131 monoclonal antibody anti-B1",
    "iodine-131 anti-B1 antibody",
    "iodine-131 anti-CD20 monoclonal antibody",
    "iodine-131 tositumomab",
    "tositumomab I-131"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iodine-i-131-tositumomab/"
}