iodine I 131 MIP-1095

{
  "id": "MLC-T-ONC-014527",
  "term": "iodine I 131 MIP-1095",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of MIP-1095, a urea-based ligand for the tumor-associated antigen (TAA) prostate-specific membrane antigen (PSMA), radiolabeled with iodine I 131 (I131), with potential antineoplastic activity. Upon administration of iodine I 131 MIP-1095, the MIP-1095 moiety selectively targets and binds to the extracellular domain of PSMA, thereby delivering cytotoxic iodine I 131 specifically to PSMA-expressing cancer cells. PSMA is a transmembrane glycoprotein that is highly expressed by malignant prostate epithelial cells and certain other tumor cells.",
  "synonyms": [
    "131I-MIP-1095",
    "MIP-1095 I-131",
    "I-131 MIP-1095",
    "(131) I-MIP-1095"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iodine-i-131-mip-1095/"
}