Iofolastat I123

{
  "id": "MLC-T-ONC-014546",
  "term": "Iofolastat I123",
  "field": "Oncology and biomedicine",
  "definition": "An iodine 123-radiolabled small molecule that exhibits high affinity for prostate-specific membrane antigen (PSMA) with potential use in molecular imaging. Iofolastat I123, a radiolabeled glutamate-urea-lysine analogue, selectively binds PSMA, which allows imaging of PSMA-expressing prostate cancer cells with gamma scintigraph. PSMA is a transmembrane glycoprotein highly expressed by malignant prostate epithelial cells and vascular endothelial cells of various solid tumors.",
  "synonyms": [
    "iodine I 123 MIP-1072",
    "123-I-MIP-1072"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iofolastat-i123/"
}