ioflubenzamide I-131

{
  "id": "MLC-T-ONC-014545",
  "term": "ioflubenzamide I-131",
  "field": "Oncology and biomedicine",
  "definition": "An iodine 131-radiolabeled small-molecule benzamide compound with potential antineoplastic activity. The benzamide moiety of ioflubenzamide I-131 binds to melanin, selectively delivering a cyotoxic dose of gamma and beta radiation to melanin-expressing tumor cells. Melanin pigments, polymer derivatives of the amino acid tyrosine, are over-expressed in approximately 40% of melanomas.",
  "synonyms": [
    "iodine I 131 MIP-1145",
    "131-I-MIP-1145"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ioflubenzamide-i-131/"
}