monoclonal antibody GD2 anti-idiotype vaccine

{
  "id": "MLC-T-ONC-015260",
  "term": "monoclonal antibody GD2 anti-idiotype vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A class of vaccines that consist of anti-idiotype monoclonal antibodies against the tumor-associated antigen disialoganglioside GD2 with potential antineoplastic activity. Vaccination with a monoclonal antibody GD2 anti-idiotype vaccine produces an immunoglobulin response against GD2 with subsequent destruction of GD2 positive tumor cells via antibody-dependent cellular cytotoxicity (ADCC). GD2 is overexpressed in melanoma, neuroblastoma, soft tissue sarcoma, and small cell carcinoma of the lung.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/monoclonal-antibody-gd2-anti-idiotype-vaccine/"
}