monoclonal antibody 4B5 anti-idiotype vaccine

{
  "id": "MLC-T-ONC-015248",
  "term": "monoclonal antibody 4B5 anti-idiotype vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A humanized anti-idiotypic (anti-Id) monoclonal antibody (MoAb) that mimics the disialoganglioside GD2 with potential immunostimulating and antineoplastic activities. Upon administration, monoclonal antibody 4B5 anti-idiotype vaccine may elicit both cellular and humoral immune responses against GD2- expressing tumor cells. GD2 is a glycosphingolipid (ceramide and oligosaccharide) that may be highly expressed by melanomas and other neuroectodermal tumors, while only minimally expressed by normal tissues.",
  "abbreviation": "MOAB 4B5",
  "synonyms": [
    "4B5 monoclonal antibody anti-idiotype vaccine",
    "MOAB 4B5 anti-idiotype vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/monoclonal-antibody-4b5-anti-idiotype-vaccine/"
}