Racotumomab
Term · Oncology and biomedicine · MLC-T-ONC-016342
An anti-idiotype murine monoclonal antibody (MoAb) specific to P3 MoAb with anti-metastatic effect. Racotumomab binds to the idiotype region of P3 MoAb and functionally mimics the three-dimensional structure of N-glycolyl ceramides of mono-sialyl lactose, the antigenic target of P3. As a result, this anti-idiotype antibody may stimulate the host immune system to elicit humoral and cellular immune responses against tumor cells expressing NeuGc-GM3 gangliosides, which are expressed in a wide variety of tumor cells.
| Identifier | MLC-T-ONC-016342 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | anti-P3 Ab idiotype mAB1E10 |
| Synonyms | anti-P3 antibody idiotype monoclonal antibody 1E10 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-016342",
"term": "Racotumomab",
"field": "Oncology and biomedicine",
"definition": "An anti-idiotype murine monoclonal antibody (MoAb) specific to P3 MoAb with anti-metastatic effect. Racotumomab binds to the idiotype region of P3 MoAb and functionally mimics the three-dimensional structure of N-glycolyl ceramides of mono-sialyl lactose, the antigenic target of P3. As a result, this anti-idiotype antibody may stimulate the host immune system to elicit humoral and cellular immune responses against tumor cells expressing NeuGc-GM3 gangliosides, which are expressed in a wide variety of tumor cells.",
"abbreviation": "anti-P3 Ab idiotype mAB1E10",
"synonyms": [
"anti-P3 antibody idiotype monoclonal antibody 1E10"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/racotumomab/"
}
Record 13,966 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.