MLchartDataset catalogue

Racotumomab

Term · Oncology and biomedicine · MLC-T-ONC-016342

An anti-idiotype murine monoclonal antibody (MoAb) specific to P3 MoAb with anti-metastatic effect. Racotumomab binds to the idiotype region of P3 MoAb and functionally mimics the three-dimensional structure of N-glycolyl ceramides of mono-sialyl lactose, the antigenic target of P3. As a result, this anti-idiotype antibody may stimulate the host immune system to elicit humoral and cellular immune responses against tumor cells expressing NeuGc-GM3 gangliosides, which are expressed in a wide variety of tumor cells.

Table 1. Record
IdentifierMLC-T-ONC-016342
FieldOncology and biomedicine
Abbreviationanti-P3 Ab idiotype mAB1E10
Synonymsanti-P3 antibody idiotype monoclonal antibody 1E10
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-016342",
  "term": "Racotumomab",
  "field": "Oncology and biomedicine",
  "definition": "An anti-idiotype murine monoclonal antibody (MoAb) specific to P3 MoAb with anti-metastatic effect. Racotumomab binds to the idiotype region of P3 MoAb and functionally mimics the three-dimensional structure of N-glycolyl ceramides of mono-sialyl lactose, the antigenic target of P3. As a result, this anti-idiotype antibody may stimulate the host immune system to elicit humoral and cellular immune responses against tumor cells expressing NeuGc-GM3 gangliosides, which are expressed in a wide variety of tumor cells.",
  "abbreviation": "anti-P3 Ab idiotype mAB1E10",
  "synonyms": [
    "anti-P3 antibody idiotype monoclonal antibody 1E10"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/racotumomab/"
}

Record 13,966 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.