Abagovomab

{
  "id": "MLC-T-ONC-009569",
  "term": "Abagovomab",
  "field": "Oncology and biomedicine",
  "definition": "A murine IgG1 monoclonal anti-idiotype antibody, containing a variable antigen-binding region that functionally mimics the three-dimensional structure of a specific epitope on the ovarian cancer tumor-associated antigen CA-125, with potential antineoplastic activity. With a variable antigen-binding region that acts as a surrogate antigen for CA-125, abagovomab may stimulate the host immune system to elicit humoral and cellular immune responses against CA-125-positive tumor cells, resulting in inhibition of tumor cell proliferation.",
  "synonyms": [
    "monoclonal antibody ACA125 anti-idiotype vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/abagovomab/"
}