Autologous cytotoxic T lymphocytes exposed to dendritic cells loaded with 6B11 anti-idiotype minibody

{
  "id": "MLC-T-ONC-011595",
  "term": "Autologous cytotoxic T lymphocytes exposed to dendritic cells loaded with 6B11 anti-idiotype minibody",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous cytotoxic T lymphocytes (CTLs) that are exposed, ex vivo, to autologous dendritic cells (DCs) loaded with the anti-idiotype minibody 6B11, which mimics the epithelial ovarian tumor-associated antigen (TAA), OC166-9, with potential immunostimulatory and antineoplastic activities. Upon administration, the CTLs exposed to DCs loaded with 6B11 anti-idiotype minibody target and kill autologous ovarian cells expressing the TAA.",
  "synonyms": [
    "autologous CTLs exposed to 6B11-OCIK",
    "autologous CTLs exposed to 6B11mini-ovarian-cytokine-induced-killer cells",
    "autologous cytotoxic T cells induced by autologous dendritic cells loaded with 6B11 anti-idiotype minibody",
    "6B11 anti-idiotype minibody-pulsed DCs induced autologous CTLs",
    "autologous CTLs induced with 6B11 anti-idiotype minibody-pulsed DCs"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-cytotoxic-t-lymphocytes-exposed-to-dendritic-cells-loaded-with-6b11/"
}