anti-GD2 monoclonal antibody BCD-245

{
  "id": "MLC-T-ONC-010686",
  "term": "anti-GD2 monoclonal antibody BCD-245",
  "field": "Oncology and biomedicine",
  "definition": "A monoclonal antibody directed against the tumor-associated antigen (TAA) disialoganglioside (GD2; GD-2), with potential antineoplastic activity. Upon administration, anti-GD2 monoclonal antibody BCD-245 may induce cytotoxicity in GD2-expressing tumor cells by antibody-dependent cell-mediated cytotoxicity (ADCC). GD2 is overexpressed on the surface of neuroblastoma (NB) cells and by other neuroectoderm-derived neoplasms, while it is minimally expressed on normal cells.",
  "synonyms": [
    "anti-GD-2 monoclonal antibody BCD-245"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-gd2-monoclonal-antibody-bcd-245/"
}