monosialotetrahexosylganglioside

{
  "id": "MLC-T-ONC-015277",
  "term": "monosialotetrahexosylganglioside",
  "field": "Oncology and biomedicine",
  "definition": "A glycosphingolipid containing a sialic acid residue found in neuronal cell membranes, with potential neuroprotective and neuroregenerative activities. Upon administration, monosialotetrahexosylganglioside, also called GM-1, is able to both prevent neurologic damage and induce regeneration of damaged neurons through neurotrophic repair mechanisms, enhancement of the production of neutrophins, and augmenting neurite outgrowth. In addition, GM-1 exerts anti-excitotoxic activity, prevents necrosis, and improves neuronal recovery and function.",
  "abbreviation": "GM1",
  "synonyms": [
    "ganglioside GM1",
    "monosialoanglioside GM1",
    "ganglioside GM-1"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/monosialotetrahexosylganglioside/"
}