Gossypol

{
  "id": "MLC-T-ONC-014012",
  "term": "Gossypol",
  "field": "Oncology and biomedicine",
  "definition": "An orally-active polyphenolic aldehyde with potential antineoplastic activity. Derived primarily from unrefined cottonseed oil, gossypol induces cell cycle arrest at the G0/G1 phase, thereby inhibiting DNA replication and inducing apoptosis. This agent also inhibits cell-signaling enzymes, resulting in inhibition of cell growth, and may act as a male contraceptive.",
  "synonyms": [
    "Cottonseed Meal Toxin",
    "Gossypol (Racemic)"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gossypol/"
}