selective estrogen receptor degrader AZD9496

{
  "id": "MLC-T-ONC-016669",
  "term": "selective estrogen receptor degrader AZD9496",
  "field": "Oncology and biomedicine",
  "definition": "An orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon administration, SERD AZD9496 binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This prevents ER-mediated signaling and inhibits the growth and survival of ER-expressing cancer cells.",
  "synonyms": [
    "SERD AZD9496"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/selective-estrogen-receptor-degrader-azd9496/"
}