selective estrogen receptor degrader SRN-927

{
  "id": "MLC-T-ONC-016671",
  "term": "selective estrogen receptor degrader SRN-927",
  "field": "Oncology and biomedicine",
  "definition": "An orally available, nonsteroidal selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon oral administration, SERD SRN-927 specifically binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This prevents ER-mediated signaling and inhibits the growth and survival of ER-expressing cancer cells.",
  "synonyms": [
    "SERD SRN-927"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/selective-estrogen-receptor-degrader-srn-927/"
}