Imlunestrant
Term · Oncology and biomedicine · MLC-T-ONC-014378
An orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon oral administration, imlunestrant specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that results in ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells.
| Identifier | MLC-T-ONC-014378 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | SERD LY3484356 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-014378",
"term": "Imlunestrant",
"field": "Oncology and biomedicine",
"definition": "An orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon oral administration, imlunestrant specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that results in ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells.",
"synonyms": [
"SERD LY3484356"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/imlunestrant/"
}
Record 9,059 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.