MLchartDataset catalogue

Imlunestrant

Term · Oncology and biomedicine · MLC-T-ONC-014378

An orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon oral administration, imlunestrant specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that results in ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells.

Table 1. Record
IdentifierMLC-T-ONC-014378
FieldOncology and biomedicine
SynonymsSERD LY3484356
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-014378",
  "term": "Imlunestrant",
  "field": "Oncology and biomedicine",
  "definition": "An orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon oral administration, imlunestrant specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that results in ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells.",
  "synonyms": [
    "SERD LY3484356"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/imlunestrant/"
}

Record 9,059 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.