Selective estrogen receptor degraderLSZ102

{
  "id": "MLC-T-ONC-016672",
  "term": "Selective estrogen receptor degraderLSZ102",
  "field": "Oncology and biomedicine",
  "definition": "A selective estrogen receptor (ER) degrader (SERD), with potential antineoplastic activity. Upon administration of LSZ102, this agent binds to the ER and induces the degradation of the receptor. This prevents ER activation and ER-mediated signaling, and inhibits the growth and survival of ER-expressing cancer cells.",
  "synonyms": [
    "SERD LSZ 102",
    "SERD LSZ102"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/selective-estrogen-receptor-degraderlsz102/"
}