saponin-cholesterol-phospholipid adjuvant

{
  "id": "MLC-T-ONC-016642",
  "term": "saponin-cholesterol-phospholipid adjuvant",
  "field": "Oncology and biomedicine",
  "definition": "An adjuvant comprised of saponin, derived from the bark of Quillaia saponaria Molina, cholesterol and phospholipid with antigen-delivery and immunostimulatory activities. This saponin-based adjuvant in combination with various antigens, including those for human papilloma virus (HPV), hepatitis C virus (HCV), and the human cancer antigen NY-ESO-1, may result in potent antibody, CD4+ T-helper-cell, and CD8+ cytotoxic T-cell responses against the targeted antigen. In addition, this agent may reduce the amount of antigen necessary to induce an efficient immune response in the host.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/saponin-cholesterol-phospholipid-adjuvant/"
}