samarium Sm 153-lexidronam pentasodium

{
  "id": "MLC-T-ONC-007543",
  "term": "samarium Sm 153-lexidronam pentasodium",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used to treat bone pain caused by bone cancer and other cancers that have spread to the bone. It contains a radioactive substance called samarium Sm 153. Samarium Sm 153-lexidronam pentasodium collects in bone and gives off radiation that may kill cancer cells. Also called Quadramet.",
    "The pentasodium salt of samarium Sm 153 lexidronam, a therapeutic agent consisting of a medium energy beta- and gamma-emitting radioisotope, samarium Sm 153, and a teraphosphonate chelator, ethylenediaminetetramethylene phosphonic acid (EDTMP). The chelator moiety of samarium Sm 153 lexidronam associates with hydroxyapatite crystals concentrated in areas of bone turnover, thereby selectively delivering samarium Sm 153-mediated cytotoxic radiation to osteoblastic bone metastases."
  ],
  "synonyms": [
    "Quadramet",
    "samarium-153 EDTMP pentasodium",
    "Sm 153 lexidronam pentasodium",
    "samarium Sm 153 lexidronam pentasodium",
    "samarium Sm-153 EDTMP pentasodium"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/samarium-sm-153-lexidronam-pentasodium/"
}